A Natural Approach to Brain Health and Cognitive Support

Alzheimer’s disease is a progressive neurological disorder that affects memory, thinking, and behavior. While current treatments aim to slow symptoms, there is no known cure. As interest in natural remedies continues to grow, CBD (cannabidiol) has gained attention for its potential neuroprotective and anti-inflammatory benefits that may support people living with Alzheimer’s disease.

In this article, we explore how CBD may be used as a complementary tool to support brain health, reduce agitation, and promote quality of life for those affected by Alzheimer’s.

Understanding Alzheimer’s Disease

Alzheimer’s is the most common cause of dementia, affecting millions of people worldwide.
It is characterized by:

  • Progressive memory loss

  • Confusion and disorientation

  • Mood swings and agitation

  • Loss of daily functioning

  • Inflammation and plaque buildup in the brain

Although medications may help manage symptoms, new and supportive therapies like CBD are being explored for additional benefit.

While there is no cure, several medications are approved in the United States and Canada to manage symptoms or modify disease progression.

Medications Approved in the United States:

  1. Cholinesterase Inhibitors:

    • Donepezil (Aricept): Approved for all stages of Alzheimer’s, it works by increasing acetylcholine levels to support memory and cognition.

    • Rivastigmine (Exelon): Used for mild to moderate stages, available in oral and transdermal forms.

    • Galantamine (Razadyne): Also for mild to moderate stages, enhances acetylcholine function.

  2. NMDA Receptor Antagonist:

    • Memantine (Namenda): Intended for moderate to severe stages, it regulates glutamate activity to protect brain cells.

  3. Combination Therapy:

    • Donepezil and Memantine (Namzaric): Combines both mechanisms for moderate to severe stages.

  4. Anti-Amyloid Antibodies:

    • Lecanemab (Leqembi): Approved for early Alzheimer’s, it targets beta-amyloid plaques to slow disease progression.

    • Donanemab (Kisunla): Also for early stages, it reduces amyloid plaques and has shown modest cognitive decline slowing.

  5. For Agitation Associated with Alzheimer’s:

    • Brexpiprazole (Rexulti): Approved to manage agitation symptoms in Alzheimer’s patients.

Medications Approved in Canada:

  1. Cholinesterase Inhibitors:

    • Donepezil (Aricept): Approved for mild to severe Alzheimer’s.

    • Rivastigmine (Exelon): For mild to moderate stages.

    • Galantamine (Reminyl ER): Also for mild to moderate stages.

  2. NMDA Receptor Antagonist:

    • Memantine (Ebixa): Approved for moderate to severe stages.

  3. For Agitation Associated with Alzheimer’s:

    • Brexpiprazole (Rexulti): Approved to manage agitation symptoms in Alzheimer’s patients.

  4. Emerging Treatments:

    • Lecanemab (Leqembi): Under review by Health Canada as of May 2023.

It’s essential for patients and caregivers to consult healthcare professionals to determine the most appropriate treatment plan, considering potential benefits and side effects.

CBD and Its Potential Benefits

CBD is a non-intoxicating compound found in the cannabis plant.
It interacts with the endocannabinoid system (ECS)—a network of receptors involved in memory, mood, inflammation, and neuroprotection.

How CBD May Help with Alzheimer’s Disease

  1. Neuroprotection:
    CBD has shown potential to protect neurons from oxidative stress and inflammation—two key contributors to Alzheimer’s progression.

  2. Reduces Inflammation:
    Chronic brain inflammation may accelerate cognitive decline. CBD’s anti-inflammatory effects may help reduce this process.

  3. Manages Anxiety and Agitation:
    CBD may help calm aggression, restlessness, and anxiety—common symptoms among Alzheimer’s patients—without the side effects of traditional sedatives.

  4. Improves Sleep and Daily Functioning:
    Better sleep can support brain health and improve mood. CBD may help regulate sleep-wake cycles in Alzheimer’s patients, enhancing daily quality of life.

CBD Dosage Guide for Alzheimer’s Support

Dosage should be approached cautiously, especially in elderly individuals. Always begin with the lowest effective dose.

Weight Mild Symptoms Moderate Symptoms Severe Symptoms
< 130 lbs 5 – 10 mg 10 – 20 mg 20 – 30 mg
130–230 lbs 10 – 20 mg 20 – 30 mg 30 – 50 mg
> 230 lbs 15 – 25 mg 30 – 50 mg 50 – 70 mg

Tips:

  • Use tinctures or oils for easy, precise dosing.

  • Begin with 5 mg and increase slowly under caregiver or medical supervision.

  • Consistency is key—effects may improve with regular use over several weeks.

  • Always consult a physician before starting CBD, especially if other medications are in use.

Frequently Asked Questions (FAQs)

Q: Can CBD treat or cure Alzheimer’s disease?
A: No. CBD is not a cure. It may help manage some symptoms and support overall brain health but should be used alongside medical care.

Q: Is CBD safe for seniors?
A: CBD is generally well tolerated, but seniors should start with low doses and consult their doctor, especially if taking other medications.

Q: Can CBD help with memory loss?
A: Research is still in early stages. CBD may help reduce inflammation and support brain function, but it cannot reverse memory loss.

Q: Will CBD make Alzheimer’s symptoms worse?
A: When used correctly, CBD is unlikely to worsen symptoms. However, dosage and product quality are important—always seek medical guidance.

Q: What’s the best way to give CBD to someone with Alzheimer’s?
A: Tinctures (liquid drops) are easy to measure and mix with food or drinks. CBD capsules or edibles may also be used, depending on the person’s needs.

Conclusion

While CBD is not a cure for Alzheimer’s disease, it may offer gentle support for symptom relief and quality of life.
From easing anxiety and agitation to supporting sleep and reducing inflammation, CBD is becoming a promising addition to holistic care strategies for Alzheimer’s patients.

As with any treatment, it’s important to consult with healthcare professionals and monitor use carefully—especially in elderly individuals with complex needs.

Note: This article is for educational purposes only and is not a substitute for professional medical advice. Always consult with your doctor before starting CBD.

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